At times in her career, she had to play forward because there were shorter players in the starting five on her team. Also, right before the 2004 season, the Mercury acquired all-star Penny Taylor in a dispersal draft, to strengthen their roster.
In her WNBA debut, Taurasi netted 26 points and led the Mercury to an 84–76 victory over the Seattle Storm.
Entering the 2014 season, Taurasi became 2nd ranked in career points per game, 5th in career points and 9th in career assists.
In the 2014 season, with a supporting cast of all-star power forward Candice Dupree (who was traded to the Mercury in 2010), rising star Brittney Griner (who was drafted 1st overall in the 2013 WNBA Draft) and the arrival of new head coach Sandy Brondello, the Phoenix Mercury finished 29-5, setting the record for most wins in a regular season, earning the top seed in the western conference.
2006 would be a historic season for Taurasi as she flourished under Westhead's system, leading the league in scoring and earning a third straight trip to the All Star Game.